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                                       羅振革    副院長百万彩票注册链接、正教授
所在學院生命科學與技術學院
研究方向神經發育與再生
聯系方式luozhg@@shanghaitech.edu.cn
備注杰青、百人


個人簡介
學習經歷
1988.7 南開大學生物工程專業 學士
1991.8  軍事醫學科學院免疫學專業 碩士
1995.7 軍事醫學科學院免疫學專業 博士

工作經歷
1991.9-1992.8 解放軍254醫院  傳染科實驗室工作人員
1995.8-1999.12 軍事醫學科學院 助理研究員、副研究員
2000.1-2003.5 阿拉巴馬大學伯明翰分校  博士后
2003.6-2018.8 中國科學院神經科學研究所 研究員百万彩票注册链接、高級研究員、所長助理百万彩票注册链接、副所長
2012-2018 上??萍即髮W  特聘教授
2014-2018 中國科學院大學 崗位教授
2018.9-至今 上??萍即髮W生命學院  正教授(Tenured)
2003年入選中科院“百人計劃,2008年獲得國家自然科學基金委杰出青年基金項目支持,2018年入選國家萬人計劃科技創新領軍人才。

主要研究內容
總目標:闡明腦結構與神經環路形成的分子細胞機制;揭示神經生長與退化相關神經系統疾病機理;開發新的神經損傷修復手段百万彩票注册链接。
主要研究內容:大腦皮層的發育與進化;神經生長與導向;突觸形成與修剪百万彩票注册链接;神經損傷與修復。  

代表性論文

1. He, M., Ding, Y.T., Chu, C., Tang, J., Xiao, Q. and Luo,  Z.G.* (2016) Autophagy induction stabilizes microtubules and promotes  axon regeneration after spinal cord injury. Proc. Natl. Acad. Sci.  USA. 113(40):11324-11329.

2. Ju, X.C., Hou, Q.Q., Sheng,  A.L., Wu, K.Y., Zhou, Y., Jin, Y., Wen, T.Q., Yang, Z.G., Wang, X.Q.,  Luo, Z.G.* (2016) The hominoid-specific gene TBC1D3 promotes  generation of basal neural progenitors and induces cortical folding in mice.  eLife. Aug 9;5. pii: e18197. doi:  10.7554/eLife.18197.

3. Wu, K.Y., Zuo, G. L., Li, X.F., Ye, Q., Deng,  Y.Q., Huang, X. Y., Wu-Chun Cao, Qin, C. F., Luo, Z.G.* (2016)  Vertical transmission of Zika virus targeting the radial glial cells affects  cortex development of offspring mice. Cell Res.  26:645-654. (Cover story, Highlighted, and received the 2016 Sanofi-Cell  Research Outstanding Paper Award).

4. Wu, K.Y., He, M., Hou, Q.Q., Sheng,  A.L., Yuan, L., Liu, Y., Liu, W.W., Li, G., Jiang, X.Y., Luo,  Z.G.* (2014) Semaphorin-3A activates the guanosine triphosphatase Rab5  to promote growth cone collapse and callosal axon projection. Sci.  Signal. 7, ra81.

5. Xu, X.H., Deng, C.Y., Liu Y., He, M.,  Peng, J., Wang, T., Yuan, L., Zheng, Z.S., Blackshear, P.J & Luo,  Z.G.* (2014) MARCKS regulates membrane targeting of Rab10 vesicles to  promote axon development. Cell Res. 24:  576–594.

6. Wang, J.Y., Chen, F., Fu, X.Q., Ding, C.S., Zhou, L., Zhang,  X.H. & Luo, Z.G.* (2014) Caspase-3 cleavage of disheveled  induces elimination of postsynaptic structures. Dev. Cell   28:670–684 (Highlighted by Preview in Developmental Cell 28,  604-606).

7. Deng, C.Y., Lei, W.L., Xu, X.H., Ju, X.C., Liu, Y. &  Luo, Z.G.* (2014) Jip1 mediates anterograde transport of Rab10  cargos during neuronal polarization. J. Neurosci.  34:1710-1723.

8. Liu, Y., Xu, X.H., Chen, Q., Wang, T.,  Deng, C.Y., Song, B.L., Du, J.L., Luo, Z.G.* (2013) Myosin Vb  controls biogenesis of post-Golgi Rab10 carriers during axon development.  Nat. Commun. 4:2005 doi:  10.1038/ncomms3005.

9. Lei, W.L., Xing, S.G., Deng, C.Y., Ju, X.C.,  Jiang, X.Y., Luo, Z.G.* (2012) Laminin/beta1 integrin signal  triggers axon formation by promoting microtubule assembly and stabilization.  Cell Res. 22:954-972.

10. Wang, T., Liu, Y.,  Xu, X.H., Deng, C.Y., Wu, K.Y., Zhu, J., Fu, X.Q., He,M., and Luo,  Z.G.* (2011) Lgl1 Activation of Rab10 Promotes Axonal Membrane  Trafficking Underlying Neuronal Polarization. Dev. Cell.  21:431-444. (Cover story and highlighted by “Faculty of 1000  Biology”).

11. Yang, G.Y., Liang, B., Zhu, J., and Luo,  Z.G.*(2011) Calpain activation by wingless-type MMTV integration site  family, member 5A (Wnt5a) promotes axonal growth. J. Biol.  Chem. 286: 6566-6576. (Highlighted by “Faculty of 1000  Biology”).

12. Wang, J., Fu, X.Q., Lei, W.L., Wang, T., Sheng, A.L.,  Luo, Z.G.* (2010) Nuclear Factor Kappa B Controls AChR  Clustering by Regulating Rapsyn Expression at the Neuromuscular Junction.  J. Neurosci. 30: 11104-11113.

13. Liang, B.,  Duan, B.Y., Zhou, X.P., Gong, J.X., Luo, Z.G.* (2010) Calpain  activation promotes bace1 expression, APP processing, and amyloid plaque  formation in a transgenic mouse model of Alzheimer disease. J Biol  Chem. 285: 27737-27744.

14. Zhou, X.P., Wu, K.Y., Liang,  B., Fu, X.Q., Luo, Z.G.*(2008) TrkB-mediated Activation of  Geranylgeranyltransferase I Promotes Dendritic Morphogenesis. Proc.  Natl. Acad. Sci. USA. 105: 17181-17186.

15. Wang, J., Ruan,  N.J., Qian, L., Chen, F., Luo, Z.G.*(2008) Wnt/β-catenin  signaling suppresses rapsyn expression and inhibits AChR clustering at the  neuromuscular junction. J. Biol. Chem. 283:  21668-21675.

16. Zhang, X., Zhu, J., Yang, G.Y., Wang, Q.J., Qian, L.,  Chen, Y.M., Chen, F., Tao, Y., Hu, H.S., Wang, T., and Luo,  Z.G.*(2007) Dishevelled promotes axon differentiation by regulating  atypical protein kinase C. Nat. Cell Biol. 9, 743-754.  (Highlighted by News and Views in the same issue of Nat. Cell Biol., “Faculty of  1000 Biology”, and Nature China).

17. Chen, F., Qian, L., Yang, Z.H.,  Huang, Y., Ngo, S.T., Ruan, N.J., Wang, J., Schneider, C., Noakes, P.G., Ding,  Y.Q., Mei, L., and Luo, Z.G.* (2007) Rapsyn interaction with  Calpain stabilizes AChR clusters at the neuromuscular junction.  Neuron 55: 247-260. (Highlighted by “Faculty of 1000  Biology”).

18. Chen, Y.M., Wang, Q.J., Hu, H.S.,Yu, P.C., Zhu, J.,  Drewes, G., Piwnica-Worms, H., Luo, Z.G.* (2006) Microtubule  affinity-regulating kinase 2 functions downstream of the PAR-3/PAR-6/aPKC  complex in regulating hippocampal neuronal polarity. Proc. Natl.  Acad. Sci. USA 103: 8534-8539.  


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